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目的:探讨氨溴索口服液联合阿奇霉素治疗小儿支原体肺炎的临床疗效。方法:124例支原体肺炎患儿随机分为两组,治疗组采用盐酸氨溴索口服液联合阿奇霉素治疗,对照组给予红霉素和小儿止咳露常规治疗。连续治疗7天,观察两组临床总有效率和不良反应率并记录病情好转时间。结果:治疗组总有效率为91.9%,对照组为85.4%,治疗组明显好于对照组(P<0.05),住院期间治疗组患儿平均退烧时间、止咳时间、肺部杂音消失时间及胸片改善状况均比对照组明显缩短(P<0.05)。两组不良反应率较小,无明显差异(P>0.05)。结论:盐酸氨溴索口服液联合阿奇霉素治疗小儿支原体肺炎疗效确切,疗程短,不良反应少,可以推广使用。
Objective: To investigate the clinical efficacy of ambroxol oral azithromycin in the treatment of children with mycoplasma pneumonia. Methods: 124 children with mycoplasmal pneumonia were randomly divided into two groups. The treatment group was treated with Ambroxol Hydrochloride oral solution and azithromycin, while the control group was treated with erythromycin and Pediatric Cough Syrup. Continuous treatment for 7 days, the two groups observed total effective rate and adverse reaction rate and record the condition improved time. Results: The total effective rate was 91.9% in the treatment group and 85.4% in the control group, which was significantly better in the treatment group than in the control group (P <0.05). The average fever time, cough time, lung murmur disappearance time and chest in the treatment group Improvements were significantly shorter than the control group (P <0.05). Two groups of adverse reaction rate was small, no significant difference (P> 0.05). Conclusion: Ambroxol hydrochloride oral azithromycin combined with azithromycin in children with mycoplasma pneumonia is effective, short course of treatment, fewer adverse reactions, can be widely used.