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目的观察对比血清脑钠肽(BNP)水平、心肌速度阶差在诊断无并发症糖尿病患者的左心室功能的临床意义。方法选取糖尿病无并发症患者100例作为试验组,同期收集来健康成年男女志愿者100例作为对照组。比较2组血清BNP、左室射血分数(LVEF)、左心室后壁收缩期心肌速度阶差(MVGs)和左心室后壁舒张期心肌速度阶差(MVGd)。结果试验组患者血清BNP高于对照组,差异有统计学意义(P<0.05)。试验组患者LVEF、MVGs和MVGd检测值均小于对照组,差异均有统计学意义(P<0.05)。结论无并发症糖尿病患者血清BNP水平高于正常人群,其左心功能亦差于正常人群,应积极预防心功能不全和糖尿病心脏病。
Objective To observe the clinical significance of comparing the level of serum brain natriuretic peptide (BNP) and myocardial velocity gradient in the diagnosis of left ventricular function in patients with non-complication of diabetes mellitus. Methods 100 cases of diabetic patients without complications were selected as the experimental group and 100 healthy volunteers were recruited as the control group. Serum BNP, left ventricular ejection fraction (LVEF), left ventricular systolic myocardial velocity (MVGs) and left ventricular posterior wall diastolic myocardial velocity gradient (MVGd) were compared between the two groups. Results The BNP level in the test group was significantly higher than that in the control group (P <0.05). The test group patients LVEF, MVGs and MVGd detection values were less than the control group, the difference was statistically significant (P <0.05). Conclusions There is no complication in patients with diabetes mellitus. The serum BNP level is higher than that in normal people. The left ventricular function is also worse than normal people. Cardiac insufficiency and diabetic heart disease should be actively prevented.