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[目的]通过对重症肺炎患儿血清心肌肌钙蛋白Ⅰ(cardiac troponinI,cTnI)和磷酸肌酸激酶同功酶(creatinephos phokinase-isoenzyme-MB,CK-MB)水平的检测,评价其在心肌损伤早期诊断中的价值。[方法]采用化学发光法和免疫抑制法检测61例合并心肌损伤的重症肺炎患儿及57例未合并心肌损伤的重症肺炎患儿血清cTnI和CK-MB水平。[结果]重症肺炎患儿心肌损伤组血清cTnI和CK-MB水平明显高于非心肌损伤组(P﹤0.05);cTnI在诊断重症肺炎合并心肌损伤的敏感度高于CK-MB;cTnI窗口时间明显宽于CK-MB。[结论]血清cTnI和CK-MB水平可作为早期诊断重症肺炎患儿心肌损伤的监测指标,且cTnI水平在诊断重症肺炎合并心肌损伤的临床价值更大。
[Objective] To evaluate the value of serum cardiac troponin I (cTnI) and creatinephos phokinase-isoenzyme-MB (CK-MB) levels in children with severe pneumonia The value of early diagnosis. [Methods] The serum levels of cTnI and CK-MB in 61 children with severe pneumonia and 57 children with severe pneumonia without myocardial injury were detected by chemiluminescence and immunosuppression. [Results] The serum levels of cTnI and CK-MB in myocardial injury group were significantly higher than those in non-myocardial injury group (P <0.05). The sensitivity of cTnI in diagnosis of severe pneumonia complicated with myocardial injury was higher than CK-MB. The cTnI window time Significantly wider than CK-MB. [Conclusion] Serum levels of cTnI and CK-MB can be used as indicators for the early diagnosis of myocardial injury in children with severe pneumonia, and the clinical value of cTnI in the diagnosis of severe pneumonia with myocardial injury is greater.