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采用 ELISA 法检测了140例肝癌患者的 HBV—M 和抗—HCV(其中38例检测了 HDV—M),并分别与56例非肝病患者和164例肝炎患者比较。结果肝癌病人中有91.2％检出 HBV—M 阳性,32.1％检出抗—HCV 阳性,HDV—M 无阳性检出。在抗—HCV 阳性的肝癌病人中,HBV—M 阳性率达95.6％。经X(?)检验分析,在 HCC 中,HBV—M、抗—HCV 和 HDV—M 的总体率两两之间均有极显著性差异。提示 HBV 与 HCC 关系最密切。HCV 次之,而 HDV 关系不明显。HCV 主要与 HBV 以重叠感染方式存在,因而推测 HCV 单独致癌的可能性不太,主要是通过调节和协同 HBV 而起促癌作用。
HBV-M and anti-HCV were detected in 140 patients with HCC by ELISA (38 of them were HDV-M), and were compared with 56 patients with non-liver disease and 164 patients with hepatitis. Results Hepatocellular carcinoma patients were positive for HBV-M in 91.2%, anti-HCV in 32.1% and negative for HDV-M. In anti-HCV positive liver cancer patients, HBV-M positive rate of 95.6%. The results of X (?) Test showed that the overall rates of HBV-M, anti-HCV and HDV-M in HCC were significantly different between any two groups. Prompt HBV and HCC most closely. HCV is the second, while the relationship between HDV is not obvious. HCV mainly exists in the form of overlapping infection with HBV. Therefore, it is speculated that HCV is not likely to be carcinogenic alone, and mainly acts as a cancer-promoting agent by regulating and coordinating HBV.