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为研究冠心汤对冠心病患者血液过氧化反应及红细胞变形性的影响，我们检测了冠心病患者使用冠心汤治疗前后红细胞SOD，全血GSH－PX、CAT活力，血浆AOA和红细胞膜MDA含量及IF的变化，结果表明，冠心病患者SOD、GSH－Px、CAT活力及AOA明显低于对照组（H＜0．01），MDA含量及IF明显高于对照组（P＜0．01）。治疗后，SOD、GSHPx、CAT活力明显高于治疗前（P＜0．05），MDA含和IF明显低于治疗前（P＜0．05，P＜0．01）。提示冠心汤能降低冠心病患者血液的过氧化反应，提高红细胞变形能力。
To investigate the effect of Guanxin Decoction on blood peroxide reaction and red blood cell deformability in patients with coronary heart disease, we detected red blood cell SOD, whole blood GSH-PX, CAT activity, plasma AOA and erythrocyte membrane MDA before and after treatment with Guanxin Decoction in patients with coronary heart disease. Changes in content and IF showed that SOD, GSH-Px, CAT activity and AOA in patients with coronary heart disease were significantly lower than those in the control group (H<0.01), and MDA content and IF were significantly higher than those in the control group (P<0.01). ). After treatment, the activities of SOD, GSHPx, and CAT were significantly higher than before treatment (P<0.05), and the levels of MDA and IF were significantly lower than those before treatment (P<0.05, P<0.01). It indicates that Guanxintang can reduce the peroxidation of blood in patients with coronary heart disease and improve the red blood cell deformability.