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对发生丙型肝炎流行的固安县不同人群的HCV感染状况进行了调查和随访。1986年献浆血员、全血血员和非献血成人的肝炎现患率分别为17.4%、1.5%和1.1%;ALT异常率分别为31.9%、7.8%和5.0%;抗—HCV阳性率分别为79.7%、12.4%和7.2%。1990年随访以上三类人群,抗—HCV阳性率分别为43.9%、6.7%和1.0%;调查献浆为主村、献全血为主村和基本不献血村全人群,抗HCV阳性率分别为22.0%、6.6%和1.4%;调查某医院供血员和妇产科病人,抗—HCV阳性率分别为46.7%和8.7%,受血者输入抗—HCV阳性和阴性血的抗—HCV阳转率分别87.8%和25.5%。以上结果表明,献浆血员为HCV高感染人群,通过输血等途径HCV感染已在一般人群中广泛传播。
The prevalence of hepatitis C in Gu’an County, different populations of HCV infection were investigated and followed up. The prevalence rates of hepatitis in plasma, blood and non-blood donors in 1986 were 17.4%, 1.5% and 1.1% respectively. The abnormal ALT rates were 31.9%, 7.8% and 5.0% respectively. The positive rates of anti-HCV were 79.7%, 12.4% and 7.2%. The positive rates of anti-HCV were 43.9%, 6.7% and 1.0% respectively in the three groups of above-mentioned population in 1990. The positive rates of anti-HCV were Were 22.0%, 6.6% and 1.4%, respectively. The positive rates of anti-HCV in hospital blood donors and obstetrics and gynecology patients were 46.7% and 8.7% respectively. The anti-HCV positive Turnover rates were 87.8% and 25.5% respectively. The above results show that plasma donors are highly HCV-infected, and HCV infection has been widely spread in the general population through transfusion and other means.