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通过测定大鼠肝细胞培养液中乳酸脱氢酶(LDH)、白蛋白及细胞内DNA的含量、探索玉米赤霉烯酮(F-2毒素)对体外培养大鼠肝细胞的损伤作用。结果表明:F-2毒素对肝细胞分泌LDH无影响,但可使白蛋白和DNA合成下降。
The effect of zearalenone (F-2 toxin) on the injury of rat hepatocytes was explored by measuring the contents of lactate dehydrogenase (LDH), albumin and intracellular DNA in rat hepatocyte culture medium. The results showed that F-2 toxin had no effect on the secretion of LDH from hepatocytes, but decreased the synthesis of albumin and DNA.