Objective To inspect the correlation of synthetic effect criteria to sensitivity,reliability of late stage lung cance r curative effect verdict and median survival time.Method Using size change of tumor,symptom c hange related to tumor,Karnofsky sc ore,body weight etc.as synthetic effect criteria and instituting clinical synthetic effect criteria,to assess the curative effec t of late stage lung cancer patients who received different treatment in department o f tumor of xiyuan hospital between Ma rch,1997and March,2000,to analysis medium survival time,and being compared with RR of tumor.Result52patients entered this experiment ,in which 42patients were assessable(follow-up),13patients were effective(30.95%),17were patients stable(40.48%),12patients deteriorated(28.57%).The result of tumor objective remis sion rate:CR is 0,PR is 16.67%(7patients),NC is 64.29%(27patients)and PD is 19.05%(8patients).There was apparent difference betw een two effect criteria(P <0.05).The mean survival time of this group is(9.3±1.6)months,median survival time is 10.5months(2～28months),survival rate of one year is 33.33%(14patients).In the patients who live longer than median survival time,most of them su rvive associated with tumor existence who are in NC of tumor objective remissio n rate,but also in the effective colu mn of synthetic effect criteria.Compared with tumor objective remis sion rate,the synthetic effect criteria have more apparent correlation to survival time.Conclusion In the assessment of late stage lung cancer,synthetic effect criteria has bett er sensitivity and reliability,and emphasize survival quality,at same time it reflect the reaction of tumor and host to treatment,it reflect prognosis of tumor preferably and have better c orrelation to the survival time.It c an be used as clinical effect criteria o f late stag lung cancer after further consummation. Objective To inspect the correlation of synthetic effect criteria to sensitivity, reliability of late stage lung cancers curative effect verdict and median survival time. Method Using size change of tumor, symptom c hange related to tumor, Karnofsky sc ore, body weight etc.as synthetic effect criteria and institing clinical synthetic effect criteria, to assess the curative effec t of late stage lung cancer patients who received different treatment in department of tumor of xiyuan hospital between Ma rch, 1997 and March, 2000, to analysis medium survival time, and being compared with RR of tumor. Result52patients entered this experiment, in which 42patients were assessable (follow-up), 13patients were effective (30.95%), 17were patients stable (40.48%), 12patients deteriorated (28.57%). The result of tumor objective remis sion rate: CR is 0, PR is 16.67% (7patients), NC is 64.29% (27patients) and PD is 19.05% (8patients). There was apparent difference betwenen two effect criteria (P <0.05) time of this group is (9.3 ± 1.6) months, median survival time is 10.5 months (2 ~ 28months), survival rate of one year is 33.33% (14patients) .In the patients who live longer than median survival time, most of them su rvive associated with tumor existence who are in NC of tumor objective remissio n rate, but also in the effective colu mn of synthetic effect criteria. Compared with tumor objective remis sion rate, the synthetic effect criteria have more apparent correlation to survival time. Conlusion In the assessment of late stage lung cancer, synthetic effect criteria has bett er sensitivity and reliability, and emphasize survival quality, at same time it reflect the reaction of tumor and host to treatment, it reflect prognosis of tumor preferably and have better c orrelation to the survival time. It c be be used as clinical effect criteria of late stag lung cancer after further consummation.