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目的 :探讨腹腔镜手术治疗卵巢成熟性畸胎瘤的疗效及应用前景。方法 :分析本院2011年12月—2014年11月接受腹腔镜手术和开腹手术治疗卵巢成熟性畸胎瘤病例,对两组患者的手术效果、手术前后白介素6(IL-6)水平和CD4+/CD8+水平进行比较。结果:腹腔镜组相对于开腹组出血量少、肛门排气时间短、术后体温恢复快、住院时间短,差异有统计学意义(P<0.05)。两组在手术时间上无明显差异(P>0.05)。两组手术患者的外周血IL-6水平和CD4+/CD8+水平在术前无显著性差异(P>0.05),在术后1 d和术后4 d差异显著(P<0.05);腹腔镜组术后4 d外周血IL-6和CD4+/CD8+水平与术前相比无显著性差异(P>0.05),而开腹组术后1 d和术后4 d与术前比较,差异均有统计学意义(P<0.05)。结论:腹腔镜手术用于卵巢成熟性畸胎瘤具有出血少、恢复快、对机体免疫功能损伤小等优点,具有良好的应用前景。
Objective: To investigate the efficacy and prospects of laparoscopic surgery for mature ovarian teratoma. Methods: The patients with mature ovarian teratoma undergoing laparoscopic surgery and open surgery from December 2011 to November 2014 in our hospital were analyzed retrospectively. The effect of surgery, the level of interleukin 6 (IL-6) CD4 + / CD8 + levels were compared. Results: Compared with the laparotomy group, the laparoscopic group had less bleeding, shorter anus exhaust time, quicker postoperative recovery of body temperature, shorter hospital stay, and the difference was statistically significant (P <0.05). There was no significant difference in operation time between the two groups (P> 0.05). The level of IL-6 and the level of CD4 + / CD8 + in the peripheral blood of the two groups were not significantly different before operation (P> 0.05), but significantly different between the first day and the fourth day after operation (P <0.05) The levels of IL-6 and CD4 + / CD8 + in peripheral blood were not significantly different at 4 days after operation (P> 0.05), while those in the open group at 1 day and 4 days after operation were significantly lower than those before operation Statistical significance (P <0.05). Conclusion: Laparoscopic surgery for the diagnosis of ovarian teratogenic anemia with less bleeding, rapid recovery, less damage to immune function, has good application prospects.