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目的 探讨原发性腹膜后肉瘤的临床处理 ,分析影响其预后因素。方法 收集 84例原发性腹膜后肉瘤患者的临床资料 ,回顾性分析其预后情况。用Kaplan -Meier法估计生存曲线 ,对可能影响患者长期存活的临床 ,病理 ,治疗方法各因素行单因素分析。结果 分级对 5年生存率有显著性影响 (P <0 .0 1)。完全切除率为 5 9.6%,完全切除后 5年生存率和 5年无瘤生存率分别是 48.1%和 3 8.8%,部分切除或活检患者 5年生存率和 5年无瘤生存率均为 0 ,两者存在高度显著性差异 (P <0 .0 0 1)。结论 肿瘤分级和手术切除是否完全是影响腹膜后软组织肉瘤预后的重要因素。对复发病例仍应积极手术治疗。限制肿瘤的假囊不应认为是安全边缘。
Objective To investigate the clinical treatment of primary retroperitoneal sarcoma and analyze its prognostic factors. Methods The clinical data of 84 patients with primary retroperitoneal sarcoma were collected and the prognosis was retrospectively analyzed. Survival curves were estimated by Kaplan-Meier method and univariate analysis was performed on all factors that may affect the long-term survival of patients with clinical, pathological, and therapeutic methods. Results The grading had a significant effect on 5-year survival rate (P <0.01). The complete resection rate was 59.6%. The 5-year survival rate and 5-year disease-free survival rate after complete resection were 48.1% and 38.8% respectively. The 5-year and 5-year disease-free survival rates of partial resection or biopsy were 0 , There is a highly significant difference between the two (P <0. 001). Conclusions Tumor classification and surgical resection are all important factors affecting the prognosis of retroperitoneal soft tissue sarcomas. Recurrence cases should still be actively treated. Tumor-restricting sacs should not be considered a safety margin.