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目的了解克罗米酚与保胎灵合用对无排卵性不孕的治疗效果。方法对无器质性病变仅表现为月经稀发,继发闭经Ⅰ度的已婚无排卵的不孕妇女随机分成两组,Ⅰ组于月经或孕酮撤药出血后的第5天口服克罗米酚,从50mg/d开始连续5d为1周期,无效,则于第二周期增加剂量,每次增加50mg/d,直至200mg/d,仍然无排卵则停止治疗;Ⅱ组服药时间如上,口服保胎灵,3粒/次,3次/d,连续服用至月经复超。结果Ⅰ组与Ⅱ组的排卵率差异无统计学意义(P>0.05);Ⅰ组LUF发生率明显高于Ⅱ组(P<0.05);Ⅰ组与Ⅱ组妊娠率差异有统计学意义(P<0.05)。结论克罗米酚与保胎灵治疗无排卵性不孕的效果差异有统计学意义。
Objective To understand the therapeutic effect of clomiphene and bao-ling together on anovulatory infertility. Methods No organic lesions showed only menstrual thinning, secondary amenorrhea Ⅰ degree of married anovulatory infertility women were randomly divided into two groups, Ⅰ group after menstruation or progesterone withdrawal bleeding on the 5th day oral g In the second cycle, the dose of romecamide increased from 50mg / d to 5mg for 1d after continuous 5d. When the dosage was increased from 50mg / d to 200mg / d, the treatment was still anovulatory. The duration of treatment in group Ⅱ was as above, Oral Pauling spirit, 3 capsules / time, 3 times / d, taken continuously to menstruation. Results There was no significant difference in ovulation rate between group Ⅰ and group Ⅱ (P> 0.05). The incidence of LUF in group Ⅰ was significantly higher than that in group Ⅱ (P <0.05). The difference of pregnancy rate between group Ⅰ and group Ⅱ was statistically significant (P <0.05). Conclusion Clomiphene and Paulingling treatment of anovulatory infertility difference was statistically significant.