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目的 研究温江县钩端螺旋体病发病率大幅下降原因 ,为防治提供科学依据。方法 传染源调查 ,人、动物血清抗体测定 ,分析与发病率关系。结果 田间啮齿目食虫目动物总带菌率、黑线姬鼠带菌率均与发病率呈正相关 (r =0 76 49、P <0 0 0 0 5 ;r=0 782 2、P <0 0 0 0 5 ) ;黑线姬鼠构成、带菌率由第 1位降为 0。自然人群抗体阳性率与发病率呈负相关 (r =- 0 16 39、P >0 0 5 ) ;自然人群抗体滴度、患者和动物中分离钩体 ,3者血清群以黄疸出血群最高 (GMT倒数平均值 =2 1 74、5 9 19%、 87 81% )。结论 黑线姬鼠是温江县钩体病主要传染源 ,其构成和田间啮齿目食虫目动物总带菌率皆降为 0 ,是该病发病率大幅下降主要原因。
Objective To study the causes of the sharp decline in the incidence of leptospirosis in Wenjiang County and to provide a scientific basis for prevention and treatment. Methods Infection source survey, human, animal serum antibody assay, analysis and incidence. Results The overall incidence of rodents in the field was positively correlated with the incidence of rodents (r = 0 76 49, P <0 0 05; r 0 782 2, P 0 100 0 5); Apodemus agrarius composition, carrier rate from the first bit down to 0. The positive rate of antibody in the natural population was negatively correlated with the incidence (r = - 0 16 39, P 0 05). The antibody titers in natural populations, the isolated leptospira in patients and animals, and the highest serogroup I jaundice GMT countdown average = 2 1 74,5 9 19%, 87 81%). Conclusion The Apodemus agrarius is the main source of leptospirosis in Wenjiang County. The composition and the total entophyla of rodents in the field are all reduced to zero, which is the main reason for the sharp decline in the incidence of the disease.