Temporal mode direct numerical simulation (DNS) has been done for a supersonic turbulent boundary layer on a flat plate with Mach number 4.5. It was found that the mean flow profile, the normal-wise distribution of turbulent Mach number and the root mean square (RMS) of the fluctuations of various variables, as well as the Reynolds stresses, bore similarity in nature, when the turbulence reached a fully developed state. But the compressibility effect was strong and must be considered. The strong Reynolds analogy (SRA) and the Morkovin hypothesis were no longer valid. From the end of transition to the fully developed state of turbulence, it was in the transient period, for which the similarity did not hold. Temporal mode direct numerical simulation (DNS) has been done for a supersonic turbulent boundary layer on a flat plate with Mach number 4.5. It was found that the mean flow profile, the normal-wise distribution of turbulent Mach number and the root mean square ( RMS) of the fluctuations of various variables, as well as the Reynolds stresses, bore similarity in nature, when the turbulence reached a fully developed state. But the compressibility effect was strong and must be considered. The strong Reynolds analogy (SRA) and the Mokovin hypothesis were no longer valid. From the end of transition to the fully developed state of turbulence, it was in the transient period, for which the similarity did not hold.