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目的评价干燥脱水法长期保存角膜片在板层治疗性角膜移植术中的效果。方法保存角膜片选自我院眼库干燥保存符合临床标准、复水透明的完整角膜片,临床病例选自我院角膜病组1976年8月～1999年12月期间行板层治疗性角膜移植患者1267例,从手术前后观力比较、原发病灶控制、植片存活情况进行临床效果综合分析。结果保存角膜片复水透明合格率为94.9％,临床治愈率:感染性角膜溃疡/穿孔88.8％,血管翳性全角膜白班98.3％.化学及热烧伤(穿孔,睑球角粘连等)92.1％,圆锥角膜及急性圆锥角膜99.5%,角膜变性(边缘性及前基质层)99.0％,其他88.9%,平均总治愈率93.5％。结论①对各种严重的角膜感染、药物治疗无法控制的患者,治疗性角膜移植术是唯一有效的方法。②采用无水氯化钙-硅胶干燥脱水长期保存的供体角膜能为临床随时提供角膜材料,是一项简单易行、便于推广应用的成功率很高的保存方法。
Objective To evaluate the effect of long-term preserved corneal dehydration in the therapeutic keratoplasty of the lamellae. Methods The preserved corneal sheets were selected from the eye bank of our hospital and were preserved in a dry cornea. The clinical cases were selected from corneal disease group of our hospital from August 1976 to December 1999. The patients were treated with platelet keratoplasty 1267 Cases, from the preoperative and postoperative contrast, primary lesion control, survival of the implant clinical analysis. Results The pass rate of reconstituted corneal rehydration was 94.9%, the clinical cure rate was 88.8% for infected corneal ulcer / perforation and 98.3% for whole corneal neovascularization.Chemical and thermal burns (perforation, eyelid angle adhesion, etc.) were 92.1% , Keratoconus and acute keratoconus 99.5%, corneal degeneration (marginal and anterior stroma) 99.0%, the other 88.9%, the average total cure rate 93.5%. Conclusion ① For all kinds of serious corneal infection, drug treatment can not control patients, therapeutic keratoplasty is the only effective method. ② The use of anhydrous calcium chloride - dehydrated silicone dehydration Long-term preservation of the donor cornea can provide corneal material at any time, is a simple and easy to promote the application of a high success rate of preservation methods.