论文部分内容阅读
目的:分析不同液体复苏方式治疗多发伤合并休克患者效果及对炎性因子的影响。方法:选取2015年1月至2017年1月东莞市人民医院收治的50例多发伤合并休克患者为研究对象,分为两组,对其进行复苏处理,对照组为积极性液体复苏,观察组为限制性液体复苏,再分别对两组患者进行手术治疗,对治疗效果进行对比分析。结果:液体复苏3 h后、24 h后,观察组患者的部分凝血活酶时间(ATPP)、凝血酶原时间(PT)短于对照组,差异具有统计学意义(P<0.05);液体复苏后24 h,观察组的氧合指数明显高于对照组,差异具有统计学意义(P<0.05);观察组的上呼吸机时间及住重症监护室(ICU)时间均低于对照组,差异具有统计学意义(P<0.05)。结论:限制性液体复苏能够有效改善多发伤合并休克患者的凝血功能紊乱等,改善临床预后。
OBJECTIVE: To analyze the effect of different liquid resuscitation methods on inflammatory response in patients with multiple trauma and shock. Methods: Fifty patients with multiple trauma and shock treated in Dongguan People’s Hospital from January 2015 to January 2017 were selected as the research object and divided into two groups. The patients were resuscitated, and the control group was active liquid resuscitation. The observation group was Restrictive fluid resuscitation, and then two groups of patients were surgically treated, the comparative analysis of the treatment effect. Results: After 3 hours of liquid resuscitation, the partial thromboplastin time (ATPP) and prothrombin time (PT) in the observation group were shorter than those in the control group after 24 hours, the difference was statistically significant (P <0.05); liquid resuscitation After 24 hours, the oxygenation index of the observation group was significantly higher than that of the control group, the difference was statistically significant (P <0.05); on the ventilator time and intensive care unit (ICU) time in the observation group were lower than the control group, the difference Statistically significant (P <0.05). Conclusion: Restrictive fluid resuscitation can effectively improve coagulation disorders in patients with multiple injuries and shock, and improve clinical prognosis.