胃肿瘤CT灌注成像的临床研究(英文)

来源 :Chinese-German Journal of Clinical Oncology | 被引量 : 0次 | 上传用户:lbj120225
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Objection:The purpose of this study is preliminarily to discuss stomach perfusion imaging technique with Multi-slice CT and its clinical application value in stomach neoplasm.Methods:Fifteen patients with known stomach neoplasm performed perfusion imaging with 4 or 16 slice CT.Performing perfusion imaging in central slice of neoplasm,using CT cine scan,slice thick 10 mm/2i;with high pressure syringe,injecting quickly from right elbow-front vein,dosage 45-50 mL,injec-tion rate 3.5-4.0 mL/s,scanning delay time 5 s,scanning total time 45 s.We performed perfusion CT post-processing using pancreatic mode of perfusion CT software.Blood flow(BF),blood volume(BV),mean transit time(MTT),and permeability surface(PS) of gastric wall and tumor were computed for every case.Results:BF,BV,MTT and PS of gastric tumor were 116.68 ± 90.09 mL/(min·100 g),9.57 ± 8.12 mL/100 g,10.07 ± 7.74 s,20.78 ± 19.68 mL/(min·100g),respectively.The P values for each CT perfusion parameters between gastric tumor and normal gastric wall were 0.001,0.021,0.155 and 0.031,respectively.Conclusion:Perfusion CT can provide hemodynamics of gastric tumors and play a key role in the diagnosis of gastric tumors.It’s clinical application prospect will be fully broad. Objection: The purpose of this study is preliminarily to discuss stomach perfusion imaging technique with Multi-slice CT and its clinical application value in stomach neoplasm. Methods: Fifteen patients with known stomach neoplasm performed perfusion imaging with 4 or 16 slice CT. Perforated perfusion imaging in central slice of neoplasm, using CT cine scan, slice thick 10 mm / 2i; with high pressure syringe, injecting quickly from right elbow-front vein, dosage 45-50 mL, injec tion rate 3.5-4.0 mL / s, scanning delay time 5 s, scanning total time 45 s. We performed perfusion CT post-processing using pancreatic mode of perfusion CT software. Blood flow (BF), blood volume (BV), mean transit time (MTT), and permeability surface ) of gastric wall and tumor were computed for every case. Results: BF, BV, MTT and PS of gastric tumor were 116.68 ± 90.09 mL / (min · 100 g), 9.57 ± 8.12 mL / 100 g, 10.07 ± 7.74 s, 20.78 ± 19.68 mL / (min · 100 g), respectively. P values ​​for each CT perfusion parameters between gastric tumor a nd normal gastric wall were 0.001, 0.021, 0.165 and 0.031, respectively. Confusion: Perfusion CT can provide hemodynamics of gastric tumors and play a key role in the diagnosis of gastric tumors. It’s clinical application prospect will be fully broad.
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