基因治疗是当今研究领域中的热点课题之一 ,其中的难点之一是如何将目标基因导入靶点———即载体的选择。近年来 ,随着研究的深入 ,已从最初的理化转染技术发展到利用各种微生物的特性达到转染目的。笔者通过对近年来国外基因治疗研究中有关载体的选择、各自的优缺点及其在不同临床治疗中的应用作一分析、比较 ,阐述了基因治疗这一新兴领域中关于载体的国外动态及其应用前景。 Gene therapy is one of the hot topics in the research field today. One of the difficulties is how to transfer the target gene into the target - that is, the choice of vector. In recent years, with the deepening of research, from the initial physical and chemical transfection technology to the use of various microorganisms to achieve the purpose of transfection. In this paper, the author analyzes and compares the advantages and disadvantages of vectors and their application in different clinical treatments in gene therapy research in recent years, and expounds the foreign dynamics of vector in this emerging field of gene therapy and its Application prospects.