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目的观察莫沙必利联合麻仁润肠丸治疗老年性便秘的疗效。方法将30例老年性便秘患者随机分为两组,各15例。对照组:麻仁润肠丸,口服,1次1丸,2次/d。大便干结,排出困难者,开始1～2d便前肛门注入开塞露。治疗组在上述治疗的基础上加用枸橼酸莫沙必利胶囊,口服,1次1粒,3次/d,饭前服用。两组在治疗期间均不应用其他影响疗效判定的药物。结果治疗组,显效5例(33.3%),有效9例(60%),无效1例(6.7%),总有效率93.3%;对照组显效4例(26.7%),有效8例(53.3%),无效3例(20%),总有效率80%;治疗组疗效明显优于对照组,且药物不良反应少,患者易于接受。结论莫沙必利联合麻仁润肠丸治疗老年性便秘疗效肯定,药物不良反应少,患者易于接受。
Objective To observe the effect of mosapride and mirenchangchang pill in the treatment of senile constipation. Methods Thirty elderly patients with constipation were randomly divided into two groups, 15 cases each. Control group: Maren Runchang pill, oral, 1 pill 1, 2 times / d. Dry stool, discharge difficulties, began 1 ~ 2d anus before the injection of open Cypriot exposed. Treatment group in the above treatment based on the addition of mosapride citrate capsules, orally, 1 time, 3 times / d, taken before meals. During the treatment of the other two groups should not be applied to determine the efficacy of other drugs. Results In the treatment group, the effective rate was 93.3% in 5 cases (33.3%), 9 cases (60%) were effective and 1 case (6.7% ), 3 cases (20%) were ineffective and the total effective rate was 80%. The curative effect of the treatment group was obviously better than that of the control group, and the side effects were less and the patients were easy to accept. Conclusion Mosapride combined with Maren Runchang pill for the treatment of senile constipation efficacy is sure, less adverse drug reactions, patients are easy to accept.