结肠黑变病(Melanosis Coli)国内报道较少,随着纤维结肠镜检查的广泛开展,其检出率会有所提高,作者发现2例,且均经病理证实,报告如下:1 病例资料 例1 女性,29岁。因便秘10余年,伴不规则脐周疼痛2月就诊。既往常服大黄苏打,潘泻叶和麻仁丸史。查体:心肺正常,腹部平软,无压痛及反跳痛,肝肋下未触及,肠鸣音减弱,结肠镜检查,横降结肠、乙状结肠,直肠粘膜为黑褐色色素呈颗粒状,网条状弥漫分布于结肠粘膜上,左半横结肠可见一花生米大小的息 Colony melanosis (Melanosis Coli) less reported in the country, with extensive screening colonoscopy, the detection rate will be increased, the authors found in 2 cases, and are pathologically confirmed, the report is as follows: 1 case data 1 female, 29 years old. Constipation for more than 10 years, with irregular umbilical pain in February treatment. In the past often served rhubarb soda, pansy leaves and Maren pill history. Physical examination: normal heart and lung, abdominal soft, no tenderness and rebound tenderness, liver ribs did not touch, bowel sounds weakened, colonoscopy, transverse colon, sigmoid colon, rectal mucosa dark brown pigment granular, Diffuse distribution in the colon mucosa, the left half of the transverse colon can be seen a peanut-sized interest