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目的:研究饮食干预联合左卡尼汀治疗维持性血液透析营养不良的疗效。方法:选取我院2012年1月到2014年1月收治的90例维持性血液透析营养不良患者,随机分为观察组和对照组,每组45例,对照组进行常规的血液透析治疗,观察组在对照组的基础上行饮食干预联合左卡尼汀的治疗,观察并对比两组患者治疗前后的疗效。结果:观察组患者治疗后体重指数(BMI)和体重增幅显著高于对照组,差异均有统计学意义(P均<0.05);观察组患者治疗后总蛋白(TP)、前白蛋白(PA)、白蛋白(Alb)显著高于对照组,血肌酐(SCr)、尿素氮(BUN)显著低于对照组,差异均有统计学意义(P均<0.05);观察组患者治疗后SGA评分显著高于对照组,差异有统计学意义(P<0.05)。结论:饮食干预联合左卡尼汀利于改善维持性血液透析营养不良患者的营养不良的症状,效果显著,值得临床推广。
Objective: To study the efficacy of dietary intervention combined with levocarnitine in maintenance hemodialysis malnutrition. Methods: Totally 90 patients with maintenance hemodialysis malnutrition admitted from January 2012 to January 2014 in our hospital were randomly divided into observation group and control group, with 45 cases in each group. The control group was treated with routine hemodialysis and observed Groups were treated with dietary intervention combined with levocarnitine on the basis of the control group. The curative effect of both groups before and after treatment was observed and compared. Results: After treatment, the body mass index (BMI) and weight gain in the observation group were significantly higher than those in the control group (all P <0.05). The total protein (TP), prealbumin ), Albumin (Alb) were significantly higher than the control group, serum creatinine (SCr), blood urea nitrogen (BUN) was significantly lower than the control group, the difference was statistically significant (P all <0.05); observation group patients after treatment SGA score Significantly higher than that of the control group, the difference was statistically significant (P <0.05). Conclusion: Dietary intervention combined with levocarnitine is beneficial to the improvement of malnutrition symptoms in patients with maintenance hemodialysis malnutrition. The results are significant and worthy of clinical promotion.