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目的观察倍美力软膏治疗老年性阴道炎的临床疗效及安全性。方法 80例老年性阴道炎患者使用倍美力软膏1次/d,两周为1疗程,停药一周后再开始第2疗程,连用两个疗程。结果用药后患者阴道健康评分明显增高,血清FSH、LH值水平显著下降,E2水平上升至卵泡早期水平(P<0.01)。用药后子宫内膜较用药前无显著变化。结论倍美力软膏能有效缓解老年性阴道炎的症状,同时无子宫内膜过度刺激,临床使用较为安全、有效。
Objective To observe the clinical efficacy and safety of Beimei Li ointment in the treatment of senile vaginitis. Methods Eighty patients with senile vaginitis were treated with Beimei Li ointment once per day for two weeks for one course of treatment. After one week of discontinuation, the second course of treatment was started and two courses of treatment were given concurrently. Results After treatment, the patients’ vaginal health scores were significantly increased, the levels of serum FSH and LH were significantly decreased, and the levels of E2 rose to the early stage of follicles (P <0.01). After treatment, the endometrium had no significant change before treatment. Conclusion Baili Li ointment can effectively alleviate the symptoms of senile vaginitis, while no endometrial over-stimulation, clinical use is safe and effective.