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目的:探讨对代谢综合征(MS)合并心血管疾病(CVD)患者实施综合干预治疗措施的效果。方法:对103例MS合并CVD患者推荐及指导综合干预治疗方案,进行相关检查,记录心血管事件发生情况,最后按是否依从干预治疗方案及是否达到标准效果分为3组(正规治疗组、非正规治疗组及未治疗组),比较3组患者的血脂、BP、FBS、颈动脉粥样斑块数与基础值的变化情况以及心血管事件、脑血管事件和死亡(排除癌症、意外死亡等)的发生情况。结果:(1)3组患者入选时观察指标基础值无统计学差异;(2)正规治疗组心血管事件发生次数及颈动脉粥样斑块数明显减少(P<0.05);(3)控制危险因素的时间越早、治疗时间越长,则控制效果越好、出现的心血管事件也越少,而且控制血压比控制血糖更为重要。结论:综合干预治疗方案是MS合并CVD患者的有效防治方案,而指导患者坚持治疗并使防治效果达标是为关键。
Objective: To investigate the effect of comprehensive intervention on patients with metabolic syndrome (MS) and cardiovascular disease (CVD). Methods: A total of 103 patients with MS complicated with CVD were enrolled in this study. The patients were followed up and instructed the interventions. The related events were recorded and the occurrence of cardiovascular events was recorded. Finally, the patients were divided into 3 groups according to their interventional treatment plan and whether they met the standard effect Regular treatment group and untreated group). The changes of blood lipids, BP, FBS, carotid artery atherosclerotic plaque count and basal values, as well as cardiovascular events, cerebrovascular events and death (excluding cancer, accidental death, etc.) were compared between the three groups ) Of the occurrence. Results: (1) There was no significant difference between the three groups on the basis of observation index (2) The number of cardiovascular events and the number of carotid artery plaque in the regular treatment group were significantly decreased (P <0.05); (3) The earlier the risk factor is and the longer the treatment is, the better the control effect is. The fewer cardiovascular events occur, and the control of blood pressure is more important than the control of blood sugar. Conclusion: The comprehensive intervention treatment is an effective prevention and treatment regimen for patients with MS complicated with CVD, and it is the key to instruct the patients to adhere to the treatment and achieve the control effect.