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目的提高PSM/HIV双重感染患者发现率,及时治疗,防止传播和蔓延。方法对某院2009年6月~2011年12月住院的1 580例HIV感染者进行PSM筛查,所有的患者均行血真菌培养,患者来自广西35个市、县。结果1 580例HIV感染者中筛查出PSM患者205例,PSM的发病率为13.0%。CD4+T淋巴细胞计数0~100/mm3时PSM的发病率为20.0%;CD4+T淋巴细胞计数100~200/mm3时PSM的发病率3.5%;CD4+T淋巴细胞计数﹥200/mm3时PSM的发病率0.7%;3者比较差异有统计学意义。结论青霉病是广西地区艾滋病患者常见机会性感染,CD4+T淋巴细胞越低PSM的发病率越高,CD4+T淋巴细胞﹤100/mm3的AIDS住院患者应常规筛查PSM,血真菌培养是简单易行可靠的筛查方法。
Objective To improve the detection rate of patients with double infection of PSM / HIV and to treat them promptly so as to prevent their spread and spread. Methods A total of 1 580 HIV-infected patients hospitalized from June 2009 to December 2011 in a hospital were enrolled in the PSM screening. All patients underwent blood fungal culture, from 35 cities and counties in Guangxi. Results A total of 205 PSM patients were screened from 1 580 HIV-infected patients. The incidence of PSM was 13.0%. The incidence of PSM was 20.0% when the CD4 + T lymphocyte count was 0-100 / mm3, the incidence of PSM was 3.5% when the CD4 + T lymphocyte count was 100-200 / mm3, and the CD4 + T lymphocyte count was> 200 / mm3 The incidence of PSM was 0.7%. The difference between the three groups was statistically significant. Conclusion Penicilliosis is a common opportunistic infection among AIDS patients in Guangxi. The lower the percentage of CD4 + T lymphocytes is, the higher the incidence of PSM and the AIDS patients hospitalized with CD4 + T lymphocytes <100 / mm3 should be routinely screened for PSM. Is a simple and reliable screening method.