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为探讨儿童重症病毒性脑炎(病毒脑)的诊断与治疗,对近十年PICU收治的28例重症病毒脑患儿进行回顾分析,28例中男13例,女15例;年龄7个月～12岁。3例明确为单纯疱疹病毒感染,2例为EB病毒感染,余无病原学证据。经应用抗病毒治疗,精制干扰素(能)100万U～300万U/天×3天～7天、三氮唑核苷10mg/(kg·d)×10天～14天、无环鸟苷5mg/(kg·次)q6h～q8h×10天～14天,及激素治疗5天～7天。结果死亡5例,脑瘫2例,智能落后2例,继发性癫痫4例,痊愈出院15例。诊治体全:诊断早晚与预后有关,EEG及CT对估计转归及预后有关,早期及时的抗病毒、激素应用及丙球治疗能改善预后
In order to explore the diagnosis and treatment of severe viral encephalitis in children, we retrospectively analyzed 28 cases of severe brain virus in PICU in recent ten years. There were 13 males and 15 females in 28 males, aged 7 months ~ 12 years old. 3 cases of clear herpes simplex virus infection, 2 cases of Epstein-Barr virus infection, I no evidence of etiology. The application of antiviral therapy, refined interferon (can) 1 million U ~ 3 million U / day × 3 days to 7 days, ribavirin 10mg / (kg · d) × 10 days to 14 days, acacia Glycosides 5mg / (kg · times) q6h ~ q8h × 10 days to 14 days, and hormone therapy for 5 days to 7 days. Results 5 cases died, 2 cases of cerebral palsy, 2 cases of intelligence behind, 4 cases of secondary epilepsy, 15 cases were discharged. Diagnosis and treatment of whole body: the diagnosis of sooner or later and the prognosis, EEG and CT on the outcome of the prognosis and prognosis, early and timely antiviral and hormonal treatment and corticosteroid treatment can improve the prognosis