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目的 探讨急性脑梗塞时载脂蛋白Ｂ与病情严重程度的预后关系。方法 对住院的急性脑梗塞患者３８７例进行分析，其中按脑梗塞严重程度分成轻、中、重三组，而对血脂和ａｐｏＡ１、ａｐｏＢ的含量进行分组对照；按入院时ａｐｏＢ高低分甲、乙、丙三组进行分析。结果 急性脑梗塞患者中有高血压病、冠心病史者占７５．１９％ ，ＴＧ和ａｐｏＢ水平在重型脑梗塞患者中明显高于中型、轻型，两者比较有非常显著性差异（Ｐ＜ ０．０１）；入院时ａｐｏＢ水平愈高，病情愈重，病死率愈高（Ｐ＜ ０．０１）。结论 载脂蛋白Ｂ水平升高是急性脑梗塞预后不良的危险因素之一。
Objective To investigate the relationship between apolipoprotein B and the severity of the disease in patients with acute cerebral infarction. Methods A total of 387 hospitalized patients with acute cerebral infarction were analyzed. According to the severity of cerebral infarction, the patients were divided into three groups according to the severity of cerebral infarction: group A, group B, group B, , C three groups for analysis. Results The patients with acute cerebral infarction had hypertension and the history of coronary heart disease accounted for 75.19%. The levels of TG and apoB were significantly higher in patients with severe cerebral infarction than those in moderate and mild type (P <0 .01). The higher the level of apoB on admission, the more serious the disease, the higher the mortality (P <0.01). Conclusion The elevated level of apolipoprotein B is one of the risk factors for poor prognosis of acute cerebral infarction.