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目的观察羟考酮缓释片单用或配合化疗对晚期肺癌疼痛的疗效。方法分析90例晚期肺癌患者,入院后根据疼痛(NRS)评分,予羟考酮缓释片口服,中度疼痛10 mg,每12小时1次;重度疼痛20 mg,每12小时1次,24 h后重新进行疼痛评分,根据评分情况调整剂量,直到疼痛控制满意。再根据有无病理诊断,有病理诊断者采取静脉化疗,无病理诊断、临床诊断明确者采取对症支持治疗。结果配合化疗的患者疼痛评分下降,没有化疗者疼痛评分增加,且需增加镇痛药物剂量。结论羟考酮缓释片配合化疗在控制疼痛方面较单纯口服镇痛治疗,在维持期控制疼痛方面,效果明显。
Objective To observe the efficacy of oxycodone sustained-release tablets alone or in combination with chemotherapy for advanced lung cancer pain. Methods Ninety patients with advanced lung cancer were enrolled. According to the pain score (NRS) after admission, they were given oxycodone sustained-release tablets orally and moderately for 10 mg once every 12 hours. Severe pain was 20 mg once every 12 hours. After h re-pain score, adjust the dose according to the score until the pain control satisfaction. According to the presence or absence of pathological diagnosis, pathological diagnosis of venous chemotherapy, no pathological diagnosis, clinical diagnosis of patients with symptomatic and supportive treatment. Results In patients with chemotherapy, the pain scores decreased, and pain scores in the absence of chemotherapy increased, and the dose of analgesics needed to be increased. Conclusion Oxycodone sustained-release tablets with chemotherapy in the control of pain than the simple oral analgesic treatment, the maintenance of pain control, the effect is obvious.