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目的观察西沙比利联用潘妥拉唑治疗胃食管反流病的临床疗效。方法将84例胃食管反流病患者随机分为两组,治疗组给予西沙比利联用潘妥拉唑治疗43例,对照组单用潘妥拉唑治疗41例,观察临床症状和内镜下表现。结果治疗组显效率为93.02%,总有效率为97.67%;对照组显效率为60.98%,总有效率为87.80%,溃疡愈合率分别为88.37%和65.85%。以上两组数据比较差异均有显著性,P<0.05。结论西沙比利联合潘妥拉唑对胃食管反流病症状改善迅速,炎症治愈率高,临床疗效优于单用潘妥拉唑,值得临床推广。
Objective To observe the clinical efficacy of cisapride combined with pantoprazole in the treatment of gastroesophageal reflux disease. Methods Eighty-four patients with gastroesophageal reflux disease were randomly divided into two groups. The treatment group received cisapride with pantoprazole in 43 cases, the control group with ptopelazole alone in 41 cases. The clinical symptoms and endoscopy Under the performance. Results The effective rate of the treatment group was 93.02%, the total effective rate was 97.67%. The effective rate of the control group was 60.98%. The total effective rate was 87.80%. The healing rates of ulcer were 88.37% and 65.85% respectively. The above two groups of data were significant differences, P <0.05. Conclusions The combination of cisapride and pantoprazole improves the symptoms of gastroesophageal reflux disease and has a high cure rate. The clinical efficacy is superior to that of the single use of pantoprazole, which deserves clinical promotion.