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目的:研究食管癌放化疗后支架置入的疗效以及置入后并发症的发生情况。方法:对先行放化疗后再行支架置入的75例晚期食管癌患者的资料进行回顾性分析,研究支架置入后吞咽功能的改善、并发症的发生及患者的死亡情况。结果:食管癌放化疗后行支架置入的患者吞咽功能改善明显,与置入前的差异具有统计学意义(P<0.05)。出院后发生穿孔3例,溃疡2例,支架脱落成脱位1例,再次梗阻死亡1例。支架置入6个月后患者死亡率为26.7%;≤40、41～50、>50岁3个年龄段的死亡率分别为7.7%、14.3%、44.1%,差异具有统计学意义(P<0.05)。结论:食管癌老年患者在食管狭窄严重的情况下,即使进行了放化疗也尽量少采用支架置入,年轻而体力允许的患者可采用支架置入,能够获得较好的生活质量。
Objective: To study the efficacy of stent implantation after radiotherapy and chemotherapy of esophageal cancer and the incidence of postoperative complications. Methods: The data of 75 patients with advanced esophageal cancer who underwent radiotherapy and chemotherapy before radiotherapy were retrospectively analyzed. The improvement of swallowing function, complication and patient’s death after stenting were studied. Results: The swallowing function of patients undergoing esophageal cancer after radiotherapy and chemotherapy was significantly improved (P <0.05). There were 3 cases of perforation after discharge, 2 cases of ulcer, 1 case of stent dislocation and dislocation, and 1 case of obstruction again. The mortality rate was 26.7% after 6 months of stenting and 7.7%, 14.3% and 44.1% respectively in the age groups of ≤40,41 ~ 50 and> 50 years, the difference was statistically significant (P < 0.05). Conclusion: In the elderly patients with esophageal cancer in the case of severe esophageal stenosis, even if the radiotherapy and chemotherapy are also used as little as possible stent implantation, young and physically allowable patients with stents can be inserted, can get a better quality of life.