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目的了解涿州市1～15岁儿童麻疹、脊髓灰质炎抗体水平,评价接种质量,为进一步做好免疫规划工作提供科学依据。方法采取随机抽样的方法采集1～15岁健康儿童血标本9 979份,使用ELISA法定量测定人血清中麻疹IgG、脊髓灰质炎IgG抗体水平。结果麻疹、脊髓灰质炎IgG抗体阳性率分别为87.9%和95.6%;不同年龄组儿童麻疹IgG抗体阳性率、脊髓灰质炎IgG抗体阳性率差异有统计学意义(χ2=22.58、χ2=27.23,P<0.05);不同性别儿童麻疹IgG抗体阳性率、脊髓灰质炎抗体阳性率差异无统计学意义(χ2=0.95、χ2=0.23,P>0.05);城区与乡镇儿童麻疹IgG抗体阳性率、脊髓灰质炎抗体阳性率差异有统计学意义(χ2=58.21、χ2=19.09,P<0.05)。结论涿州市1～15岁儿童麻疹、脊髓灰质炎抗体水平保持在较高水平,麻疹IgG抗体、脊髓灰质炎抗体阳性率随年龄的增长显著降低,城区儿童麻疹、脊髓灰质炎抗体水平显著高于农村。
Objective To understand the measles and poliomyelitis antibody levels in children aged 1-15 years in Pizhou City and evaluate the vaccination quality so as to provide a scientific basis for further immunization planning. Methods A total of 9 979 blood samples were collected from healthy children aged 1-15 years by random sampling method. The levels of measles IgG and poliomyelitis IgG in human serum were determined by ELISA. Results The positive rates of measles and poliomyelitis IgG were 87.9% and 95.6% respectively. The positive rate of measles IgG and the positive rate of polio IgG in children of different age groups were statistically significant (χ2 = 22.58, χ2 = 27.23, P <0.05). The positive rate of measles IgG and the positive rate of poliomyelitis in children of different sex were not significantly different (χ2 = 0.95, χ2 = 0.23, P> 0.05). The positive rates of measles IgG in children and urban children, The positive rate of inflammation antibody was statistically significant (χ2 = 58.21, χ2 = 19.09, P <0.05). Conclusion The measles and poliomyelitis antibody levels in children aged 1-15 years in Danzhou kept a high level. The positive rate of measles IgG and poliomyelitis antibody was significantly decreased with age, and the measles and poliomyelitis antibody levels in urban children were significantly higher Countryside.