1981年 Siegl 等提出了“红细胞免疫系统的新概念,指出红细胞不仅具有呼吸功能,而且备免疫功能。人体血循环中的C_3b 受体有95%位于红细胞膜上,红细胞通过 C_3b 受体清除免疫复合物的能力是白细胞的500～1000倍。并证明自家免疫性疾病患者红细胞粘附免疫复合物能力高。但布氏菌病(以下简称布病)病人红细胞免疫功能如何尚未见到报导。 In 1981, Siegl et al proposed "a new concept of erythrocyte immune system, pointing out that erythrocytes not only have respiratory function but also immune function, 95% of C_3b receptors in human blood circulation are located on the erythrocyte membrane, and red blood cells remove immune complexes through C_3b receptors Is 500 to 1000 times more effective than white blood cells and proves that patients with autoimmune diseases have a high ability to adhere erythrocytes to immune complexes, but how erythrocyte immune function has not been reported in patients with brucellosis (hereinafter referred to as brucellosis).