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急性早幼粒细胞性白血病(简称APL)是急粒的一种特殊类型,常因严重出血而致命。末梢血和骨髓中有异型早幼粒细胞,含有嗜天青粗颗粒;血小板减少,常反映为弥散性血管内凝血的凝血象。本病约占所有急性白血病的6％或急粒的13％。本病无临床特点,唯常见出血征如紫癜、鼻衄、尿血、牙龈或胃肠道出血,经常因脑出血而死亡。肝、脾、淋巴结肿大者少见,牙龈萎缩和皮肤浸润亦不常见。
Acute promyelocytic leukemia (APL) is a special type of acute pellet, often fatal due to severe bleeding. Peripheral blood and bone marrow in the shape of promyelocytic, containing addicted coarse particles; thrombocytopenia, often reflected as diffuse intravascular coagulation coagulation. The disease accounts for about 6% of all acute leukemia or acute granuloma 13%. No clinical features of this disease, the only common signs of bleeding such as purpura, epistaxis, hematuria, gums or gastrointestinal bleeding, often due to cerebral hemorrhage and death. Liver, spleen, lymph nodes are rare, gingival recession and infiltration of the skin are not common.