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目的:探讨益心舒胶囊配伍硝酸异山梨酯片治疗心绞痛患者的临床效果。方法:选取本院2013年6月-2014年7月收治的心绞痛患者86例作为研究对象,使用随机数字表法分为观察组以及对照组各43例。其中对照组给予单独硝酸异山梨酯片治疗,观察组给予益心舒胶囊配伍硝酸异山梨酯片治疗,观察两组患者治疗效果,统计两组患者不良反应发生率、治疗前后心绞痛发作频率、持续时间等临床指标。结果:观察组患者治疗有效率95.3%,对照组患者治疗有效率76.7%,两者比较,差异具有统计学意义(P<0.05)。两组患者治疗前后心绞痛发作频率以及持续时间均有所改善比较,差异具有统计学意义(P<0.05),同时观察组患者改善程度明显优于对照组比较,差异具有统计学意义(P<0.05)。两组患者均无明显头痛、头晕、皮肤改变等不良反应。结论:益心舒胶囊配伍硝酸异山梨酯片治疗心绞痛患者有着良好的临床疗效,能够显著减少患者心绞痛发作频率和持续时间,同时安全性高。
Objective: To investigate the clinical effect of Yixinshum capsules combined with isosorbide dinitrate tablets in the treatment of patients with angina pectoris. Methods: Totally 86 patients with angina pectoris who were admitted to our hospital from June 2013 to July 2014 were selected as the research object. The random number table was divided into observation group (43 cases) and control group (43 cases). The control group was treated with isosorbide dinitrate alone. The observation group was treated with Yixinshu capsule and isosorbide dinitrate tablets. The therapeutic effect was observed in both groups. The incidence of adverse reactions, the frequency of angina pectoris before and after treatment were recorded Time and other clinical indicators. Results: The effective rate of the treatment group was 95.3% in the observation group and 76.7% in the control group, the difference was statistically significant (P <0.05). The frequency of angina pectoris and the duration of angina pectoris before and after treatment in both groups were significantly improved (P <0.05), and the improvement in the observation group was significantly better than that in the control group (P <0.05) ). Two groups of patients had no obvious headache, dizziness, skin changes and other adverse reactions. Conclusion: Yixinshu capsules with isosorbide mononitrate tablets in patients with angina pectoris have a good clinical efficacy, can significantly reduce the frequency and duration of angina pectoris patients, while high safety.