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碳苷类化合物早在四十年前就已合成。Sharma等发现了碳苷类抗菌素,进一步研究表明,一般具备生理活性的碳苷类化合物的端基C(1)-C’键多属β型。从而引起人们研究碳苷的兴趣。近年来,Hurd等报道了一些吡喃糖碳苷化合物的研究。呋喃糖环上的键取向多为半竖键或半横键,形成糖环上相邻碳原子与氢原子间的键角不稳定,使两个异构体间的能量差小,较难分离,所以对呋喃糖的研究不多。Kalvoda在研究呋喃核糖芳烃碳苷的端
C-glycosides have been synthesized as early as 40 years ago. Sharma et al. Discovered the C-glycosidic antibiotics. Further studies showed that the terminal C (1) -C ’bonds of the commonly physiologically active C-glycosides are mostly β-type. Thus causing people to study the interest of carbon glycosides. In recent years, Hurd et al. Reported some studies on pyranose carbon glycoside compounds. Furan sugar ring key orientation mostly semi-vertical key or half-horizontal key, the formation of sugar ring adjacent carbon atoms and hydrogen atoms between the bond angle instability, the energy difference between the two isomers, the more difficult to separate , So little research on furanose. Kalvoda is studying the end of ribofuranosidc C-glycosides