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目的:探讨临床药师干预对门冬氨酸钾镁注射液合理使用的影响。方法:对2013年第四季度和2014年第二季度应用门冬氨酸钾镁注射液的门、急诊处方进行收集与分析,比较干预前后该药使用情况的变化。结果:干预前用药不合理的处方占35.4%,干预后用药不合理的处方占15.8%,差异有统计学意义(P<0.01)。干预后门冬氨酸钾镁注射液在超适应证用药、药液浓度过高、配伍不合理方面与干预前相比差异均有统计学意义(P<0.01或P<0.05)。结论:临床药师对门冬氨酸钾镁注射液的干预是有效的,且仍需持续干预。
Objective: To investigate the effect of clinical pharmacist intervention on rational use of potassium-magnesium aspartate injection. Methods: The door and emergency prescriptions for potassium-magnesium aspartate injection in the fourth quarter of 2013 and the second quarter of 2014 were collected and analyzed, and the change of the use of the drug before and after the intervention was compared. Results: Before the intervention, 35.4% of the prescriptions were irrational and 15.8% of the prescriptions were used after the intervention. The difference was statistically significant (P <0.01). After intervention, the potassium-magnesium aspartate injection had significant difference (P <0.01 or P <0.05) compared with that before intervention in the indications of super-indications, the high concentration of drug solution and unreasonable compatibility. Conclusion: The intervention of clinical pharmacists on potassium-magnesium aspartate injection is effective and requires continuous intervention.