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目的探讨标准化位点注射A型肉毒毒素(BTX-A)治疗颜面部痉挛的有效性、疗效一致性及安全性。方法标准化控制肉毒毒素注射位点的范围,分析连续3轮次治疗的有效率、症状缓解程度及不良反应等。结果共60例颜面部痉挛患者接受了连续3轮次治疗,治疗有效率分别为95.8%、96.4%和98.3%,不良反应率分别为21.7%、21.4%和20.8%。3轮次治疗的起效时间、维持时间、有效率及不良反应率间的差异均无统计学意义(P>0.05)。结论标准化位点注射肉毒毒素治疗颜面部痉挛患者疗效确切,多次重复疗效一致、不良反应轻微。
Objective To investigate the efficacy, efficacy and safety of standard site injection of botulinum toxin type A (BTX-A) in the treatment of facial spasm. Methods Standardization of botulinum toxin injection site range, analysis of three consecutive rounds of treatment efficiency, symptom relief and adverse reactions. Results A total of 60 cases of facial spasm were treated with three consecutive treatments. The effective rates were 95.8%, 96.4% and 98.3% respectively. The adverse reaction rates were 21.7%, 21.4% and 20.8% respectively. There was no significant difference in the onset time, maintenance time, effective rate and adverse reaction rate between the three rounds of treatment (P> 0.05). Conclusion The standardized site of botulinum toxin in the treatment of facial spasm is effective, repeated multiple curative effect, minor adverse reactions.