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大肠血吸虫病并发大肠癌23例,发病年龄平均51.1岁,症状多为腹痛、腹泻、便血,发病部位大肠各肠段都有,直肠10例(43%),可能与血吸虫病灶在大肠的分布有关。癌组织分化较好,管状腺癌占47.8%,粘液腺癌仅占13%。多数病例癌组织中和癌组织边缘都有大量虫卵沉积,且癌组织外虫卵结节和虫卵沉积处肠粘膜上皮有异型增生现象,提示虫卵沉积与癌的发生有因果关系。
There were 23 cases of colorectal cancer complicated by schistosomiasis. The average age of onset was 51.1 years. Most of the symptoms were abdominal pain, diarrhea, and blood in the stool. There were 10 cases of rectum in the rectum (43%), which may be related to schistosomiasis lesions in the large intestine. Distribution related. The cancer tissue was well differentiated, with 47.8% of tubular adenocarcinomas and only 13% of mucinous adenocarcinomas. In most cases, there are a large number of eggs deposited in the cancerous tissues and at the edge of the cancerous tissue, and there are dysplasias in the intestinal mucosal epithelium outside the cancerous tissue egg nodule and the egg deposition, suggesting a causal relationship between the egg deposition and the occurrence of cancer.