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肝脏是许多恶性肿瘤常见的转移器官之一,单发的转移结节可以积极外科手术治疗,但弥漫性的多发肝转移结节缺乏有效的治疗方法。近几年来免疫治疗、基因治疗为肝转移肿瘤的治疗开辟了新的路径。而白细胞介素12(IL-12)被认为是细胞免疫应答过程中的关键调节因子,具有明显的抗肿瘤?
The liver is one of the most common metastatic organs in many malignancies. Solitary metastatic nodules can be actively surgically treated, but diffuse multiple hepatic metastatic nodules lack effective treatment. In recent years, immunotherapy, gene therapy for the treatment of liver metastases has opened up a new path. Interleukin-12 (IL-12) is considered as a key regulator of cellular immune response and has obvious anti-tumor effect.