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目的评价泉州市2009年麻疹疫苗(MV)强化免疫效果,为消除麻疹提供依据。方法对MV强化免疫接种率、人群麻疹抗体水平监测和2006～2010年疫情资料进行分析。结果 2009年泉州市8个月-14岁儿童1231987名,MV强化免疫接种率为99.04%。强化免疫后麻疹抗体阳性率上升到100%,几何平均滴度(GMT)由1∶6918.31增长到1∶11220.18;经过一年流行病学观察,麻疹疫情得到有效控制,,2009年4月～2010年3月发病率下降到0.09/10万,比前三年同期平均发病水平下降了98.74%。结论泉州市2009年MV强化免疫效果显著,高质量的MV强化免疫是迅速控制麻疹发病的重要措施。
Objective To evaluate the 2009 2009 measles vaccine (MV) to strengthen the immune effect, to provide the basis for the elimination of measles. Methods The rates of intensive immunization (MV) immunization, measles antibody surveillance in human population and epidemiological data from 2006 to 2010 were analyzed. Results In 2009, there were 123,1987 children aged 8 months to 14 years in Quanzhou. The rate of MV immunization was 99.04%. After the booster immunization, the positive rate of measles antibody increased to 100% and the geometric mean titer (GMT) increased from 1:6918.31 to 1: 11220.18. After one year of epidemiological observation, the measles outbreak was effectively controlled. From April 2009 to 2010 The incidence in March dropped to 0.09 / 100,000, down 98.74% over the previous three years. Conclusions In 2009, the effect of MV enhancement in Quanzhou was significant. High-quality MV enhancement immunity was an important measure to control the incidence of measles rapidly.