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目的:探讨125I粒子植入治疗中晚期肺癌的临床应用可行性。材料和方法:对58例中晚期肺癌实施TPS模拟、CT定位下行病灶内放射性粒子植入术。术后3~8个月定期临床随访,3个月后全部行CT或胸部X线平片复查。结果:鳞癌28例,完全缓解2例,部分缓解19例,微效2例,无变化5例,有效率82.1%。腺癌9例,完全缓解0例,部分缓解4例,微效3例,无变化2例,有效率77.7%。小细胞癌21例,完全缓解3例,部分缓解10例,微效5例,无变化2例,有效率85.7%。结论:多数中晚期肺癌125I粒子植入治疗后取得良好近期疗效。
Objective: To investigate the clinical application of 125I seed implantation in the treatment of advanced lung cancer. MATERIALS AND METHODS: TPS was performed on 58 cases of advanced lung cancer. CT localization was performed in the lesion with radioactive particle implantation. After 3 to 8 months of regular clinical follow-up, 3 months after all the line CT or chest X-ray review. Results: There were 28 cases of squamous cell carcinoma with complete remission in 2 cases, partial remission in 19 cases, slight effect in 2 cases, no change in 5 cases, and the effective rate was 82.1%. Adenocarcinoma in 9 cases, complete remission in 0 cases, partial remission in 4 cases, 3 cases of microeffects, no change in 2 cases, the effective rate was 77.7%. Small cell carcinoma in 21 cases, complete remission in 3 cases, partial remission in 10 cases, 5 cases of microeffects, no change in 2 cases, the effective rate was 85.7%. Conclusion: The majority of advanced lung cancer with 125I seeds implantation has achieved good short-term efficacy.