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对161例住院的呼吸道感染患儿同时检测CVB-Ag和CVB-IgM,结果发现阳性者94例,其中CVB-Ag阳性率30.43%(49/161),CVB-IgM阳性率45.96%(74/161),29例两者均阳性。3组平均发病天数分别为4.2±2.5、15.7±8.2和8.1±3.2,前组分别与后2组相比有显著差异(P<0.01和P<0.05)。结果表明,CVB是儿童呼吸道感染的常见病原体;将CVB-Ag和CVB-IgM联合检测,可提高CVB感染的检出率。
CVB-Ag and CVB-IgM were detected in 161 hospitalized children with respiratory tract infection. The positive rate of CVB-Ag was 30.43% (49/161) and the positive rate of CVB-IgM was 45.96% 74/161), 29 were positive for both. The average days of onset in the three groups were 4.2 ± 2.5, 15.7 ± 8.2 and 8.1 ± 3.2, respectively. There were significant differences (P <0.01 and P <0.05) between the former group and the latter two groups respectively. The results showed that CVB is a common pathogen of respiratory tract infection in children. Combined detection of CVB-Ag and CVB-IgM can improve the detection rate of CVB infection.