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目的：初步评价９９ Ｔｃｍ 甲氧异丁基异腈（ Ｍ Ｉ Ｂ Ｉ）闪烁显像对骨良恶性疾病的鉴别诊断的临床价值． 方法：对６１ 例临床拟诊的骨良恶性病变患者，分别给予静脉“弹丸”注射９９ Ｔｃｍ Ｍ Ｉ Ｂ Ｉ７４０ Ｍ Ｂｑ，即刻行早期血流显像和３０ ｍ ｉｎ～６０ ｍ ｉｎ病灶局部平面扫描． 结果分析用肉眼判断和 Ｒ Ｏ Ｉ技术计算病变部位与对侧相应部位计数比值． 所有患者２ ｗ ｋ～４ ｗ ｋ 后行手术治疗，并做病理检查对比． 结果：肉眼分析发现，大部分恶性骨肿瘤病灶（７３％ ，３０／４１ 例）在动脉血流灌注相和３０ ｍ ｉｎ～６０ ｍ ｉｎ 平面相中显示了９９ Ｔｃｍ Ｍ Ｉ Ｂ Ｉ中高度浓集． 小部分患者显示了轻度９９ Ｔｃｍ Ｍ Ｉ Ｂ Ｉ聚集． 仅有３ 例和２ 例患者病灶组织分别在动脉血流相和 ３０ ｍ ｉｎ ～６０ ｍ ｉｎ 平面相时未明确显示９９ Ｔｃｍ Ｍ Ｉ Ｂ Ｉ浓聚影． 大部分良性骨及软组织病灶（６０％ ，１２／２０ 例），在血流灌注相或３０ ｍ ｉｎ～ ６０ ｍ ｉｎ 平面像均未见９９ Ｔｃｍ Ｍ Ｉ Ｂ Ｉ浓聚影，但有 ３０％ （６／２０ 例）显示中度放射性浓聚，１０％ （２／２０ 例）显示轻度放射性浓聚． 定量分析表明：在早期血流灌注相，恶?
Objective: To evaluate the clinical value of 99 Tcm methoxyisobutylisonitrile (M I B I) scintigraphy in differential diagnosis of benign and malignant bone diseases. Methods: Sixty-one patients with clinically suspected benign and malignant bone lesions were treated with intravenous injection of 99 Tcm M I B I740 M Bq, immediate early blood flow imaging and focal plane of 30 m in ~ 60 m in lesions scanning. Results Analysis with the naked eye and R O I technique to calculate the lesion site and the corresponding contralateral contralateral contralateral ratio. All patients underwent surgical treatment after 2 wk ~ 4 wk, and compared with pathological examination. Results: Macroscopic analysis showed that most of the malignant bone tumor lesions (73%, 30/41) showed 99 Tcm M I B I mid-height in the arterial perfusion phase and 30 m in ~ 60 m in planar phase Concentrate. A small number of patients showed mild 99 Tcm M I B I aggregation. The lesions of 99 Tcm M I B I did not show clearly in the arterial blood flow phase and in the plane of 30 m in ~ 60 m in only 3 and 2 patients, respectively. Most of benign bone and soft tissue lesions (60%, 12/20 cases) showed no 99 Tcm M I B I concentration in the perfusion phase or 30 m in ~ 60 m in. However, 30% (6/20 cases) showed moderate radioactive buildup and 10% (2/20 cases) showed mild radioactive buildup. Quantitative analysis showed that: in the early perfusion phase, evil?