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目的探讨人类巨细胞病毒(CMV)感染与流产、死(畸)胎、肾炎、脑炎和诊断不明发热(无名热)关系,对以上643例患者和60例对照者CMV感染状态进行了调查分析。方法应用酶联免疫吸附试验(ELISA)检测CMV-IgM特异性抗体。结果 CMV-IgM抗体阳性率病人组18.2%(117/643),对照组1.7%(1/60)。两组阳性率比较,差异有统计学意义(χ2=10.735P<0.01)。结论 CMV感染与流产、死(畸)胎、肾炎、脑炎和无名热等疾病的部分患者发病有关。
Objective To investigate the relationship between human cytomegalovirus (CMV) infection and miscarriage, dead fetus, nephritis, encephalitis and unknown fever (anonymous fever), and to investigate the status of CMV infection among 643 patients and 60 controls . Methods CMV-IgM specific antibodies were detected by enzyme linked immunosorbent assay (ELISA). Results The positive rate of CMV-IgM antibody was 18.2% (117/643) in the patient group and 1.7% (1/60) in the control group. The positive rate of the two groups, the difference was statistically significant (χ2 = 10.735P <0.01). Conclusion CMV infection is associated with the onset of some patients with miscarriage, dead fetus, nephritis, encephalitis and anonymous fever.