简单催化模型的改进及在乙型肝炎感染中的应用

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简单催化模型常用于确定易感人群年新感染率与感染率之间的关系,但局限于易感人群年新感染率与年龄无关.为解决此局限性,对模型做了相应的改进,并应用于1992年肝炎流行病学调查中乙型肝炎病毒感染宰的拟合,结果表明,改进模型比简单催化模型优越。 Simple catalytic models are often used to determine the relationship between the rate of new infections and the rate of infection in susceptible individuals, but the annual rate of new infections, which is confined to susceptible populations, is age-independent. In order to solve this limitation, the model was improved correspondingly and applied to the fitting of hepatitis B virus infection in hepatitis epidemiology survey in 1992. The results show that the improved model is superior to the simple catalytic model.
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