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目的 研究放射活性10 3钯 ( 10 3Pd)粒子近距离照射各种肿瘤的治疗效果及应用价值 .方法 31例确诊为恶性肿瘤患者通过不同方式植入10 3Pd粒子 ,观察肿瘤大小变化、局部复发和远处转移情况 ;并按RTOG/EORTC急性或后期放疗副作用评分标准进行评分 .结果 近期疗效观察理想 ,副作用小 ,安全可行 .RTOG/EORTC评分 0分有 2 8/31例 .2 /31例死亡患者在行此治疗前均已经发生远处转移 ,最后死于重要脏器衰竭 .结论 10 3Pd粒子适用于对射线低至中性敏感的肿瘤永久性植入治疗
Objective To study the therapeutic effect and application value of radioactive 10 3 Pd (10 3 Pd) particles in short-term irradiation of various tumors.Methods Totally 101 patients with malignant tumor were implanted with 103Pd particles in different ways to observe the changes of tumor size, And distant metastasis.All patients were scored according to RTOG / EORTC criteria of acute or postoperative radiotherapy side effects.Results The recent curative effect was ideal and the side effects were small and safe.RTOG / EORTC score was 2 8/31 with 2/31 deaths The patient had had a distant metastasis prior to this treatment and eventually died of an important organ failure.Conclusion 10 3Pd particles are suitable for permanent neoplasms with low to moderate radiation sensitivity