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目的：以组织形态计量学的方法，分析运动对切除卵巢前后大鼠骨代谢的影响，并与钙和激素进行比较。方法：切除卵巢大鼠分成正常对照组、模型组、运动组，运动十钙联合组、运动１组、运动２组、服钙组、雌激素组和制动组。检测各组骨组织形态计量学和骨密度。结果：骨组织形态计量学指标显示，运动各组的各项成骨指标最优，制动组最差，模型组、服钙组和激素组相互比较差异无显著性；实验各组骨密度测定结果显示同样的变化趋势。结论：切除卵巢前的运动可增加大鼠骨的储备量，切除卵巢后的运动可减缓大鼠骨量的丢失，有利于保持大鼠的骨量。运动作为一种简单实用的方法，对绝经后妇女的骨质疏松症可起到有效的防治作用。
OBJECTIVE: To analyze the effect of exercise on bone metabolism in ovariectomized rats by histomorphometry and compare with calcium and hormone. Methods: The ovariectomized rats were divided into normal control group, model group, exercise group, exercise plus calcium group, exercise group 1, exercise group 2, calcium group, estrogen group and brake group. The bone histomorphometry and bone mineral density of each group were detected. Results: Bone histomorphometry showed that the osteogenesis index of each group was the best, the brake group was the worst, and there was no significant difference between the model group, the calcium group and the hormone group. The bone mineral density The results show the same trend. CONCLUSION: Pre-ovariectomized exercise can increase the reserve of bone in rats, and exercise after ovariectomy can reduce the loss of bone mass in rats and maintain the bone mass of rats. Exercise as a simple and practical method for postmenopausal women with osteoporosis can play an effective prevention and treatment.