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目的探讨孤独症谱系障碍(autism spectrum disorder,ASD)儿童的父母焦虑抑郁状态变化及对儿童康复干预成效的影响。方法对2009年1月-2011年12月在该院确诊的孤独症儿童48例及其父母96名分别进行孤独症行为量表(Autism Behavior Checklist,ABC)、儿童期孤独症评定量表(The Childhood Autism Rating Scale,CARS)、抑郁自评量表(Self-rating Depression Scale,SDS)和焦虑自评量表(Self-rating Anxiety Scale,SAS)评估,并在2014年12月-2015年3月期间对上述儿童及其家长进行第2次评估。由于纵向研究时间较长,部分脱落,最终实际调查孤独症儿童40例及其父母80名。结果 ASD儿童初评ABC、CARS得分为(103.96±31.85)分、(37.96±4.90)分,复评(95.50±26.79)分、(35.45±5.40)分,复评得分显著低于初评得分(t=2.57,P<0.05;t=4.475,P<0.01);父亲SDS、SAS初评得分(46.05±12.00)分、(37.20±9.21)分,复评(45.3±11.60)分、(38.15±8.57)分,初复评比较差异无统计学意义(t=0.50,P>0.05;t=-0.94,P>0.05);母亲SDS、SAS初评得分(46.35±12.18)分、(39.58±12.30)分,复评(45.03±13.11)分、(41.70±12.28)分,初复评比较差异无统计学意义(t=0.71,P>0.05;t=-1.26,P>0.05)。母亲SAS初评分与ASD儿童CARS变化值有相关性(r=-0.351,P<0.05);父亲SAS初评分、母亲SAS、母亲SDS初评分与ASD儿童ABC变化值有相关性(r=-0.323,P<0.05;r=-0.328,P<0.05;r=-0.368,P<0.05)。结论孤独症儿童阶段性干预成效显著,但是父母的焦虑抑郁状态持续存在,并对儿童康复干预成效产生显著影响。
Objective To investigate the changes of anxiety and depression status in parents of children with autism spectrum disorder (ASD) and their effects on rehabilitation intervention in children. Methods Autism Behavior Checklist (ABC), Children Autism Rating Scale (The Autism Behavior Checklist, 48) and their parents were enrolled in this study. Among 48 autistic children and 96 parents diagnosed in the hospital from January 2009 to December 2011, Childhood Autism Rating Scale (CARS), Self-rating Depression Scale (SDS) and Self-rating Anxiety Scale (SAS), and from December 2014 to March 2015 During the second assessment of these children and their parents. As a result of the longitudinal study for a long time, part of the fall, the final survey of 40 cases of autistic children and their parents 80. Results The scores of ABC and CARS in children with ASD were (103.96 ± 31.85), (37.96 ± 4.90), (95.50 ± 26.79) and (35.45 ± 5.40) respectively, and the score of re-evaluation was significantly lower than the score of initial evaluation (P <0.05; t = 4.475, P <0.01). The father’s initial evaluation score of SDS and SAS was 46.05 ± 12.00, 37.20 ± 9.21, 45.3 ± 11.60, 38.15 ± 8.57, There was no significant difference between the two groups (t = 0.50, P> 0.05; t = -0.94, P> 0.05) ) Points, (41.70 ± 12.28) points, no significant difference in the first re-evaluation (t = 0.71, P> 0.05; t = -1.26, P> 0.05). There was a significant correlation between the SAS score of mothers and the CARS of children with ASD (r = -0.351, P <0.05) , P <0.05; r = -0.328, P <0.05; r = -0.368, P <0.05). Conclusions The interventional effect of autism in children is remarkable. However, anxiety and depression of parents persist, and have a significant impact on the effectiveness of rehabilitation intervention in children.