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目的 探索经面罩间歇负压通气对慢性阻塞性肺部疾病呼吸肌疲劳的治疗作用。方法 对慢性阻塞性肺部疾病 (COPD)患者进行面罩间歇负压通气 ,利用微型负压调节泵使呼气相负压值为 - 5cmH2 O ,每天通气 1h ,连续应用 7d ,观察患者的肺功能、动脉血气、呼吸肌肌力改变。结果 与对照组相比 ,治疗组COPD患者的MEP、FEV1.0 、FEV1.0 %、MVV、PaCO2 均有显著性改善 (P <0 .0 5 )。结论 面罩间歇负压通气对慢性阻塞性肺部疾病呼吸肌疲劳有较为肯定的治疗作用
Objective To explore the therapeutic effect of intermittent negative pressure ventilation on respiratory muscle fatigue in patients with chronic obstructive pulmonary disease. Methods Intermittent negative pressure ventilation was performed in patients with chronic obstructive pulmonary disease (COPD). The negative pressure of expiratory phase was adjusted to - 5cmH2O with a miniature negative pressure regulating pump. Ventilation was performed for 1 hour daily for 7 days. Lung function Arterial blood gas, respiratory muscle strength changes. Results Compared with the control group, MEP, FEV1.0, FEV1.0%, MVV and PaCO2 in COPD patients in the treatment group were significantly improved (P <0.05). Conclusion Facial mask intermittent negative pressure ventilation has more positive therapeutic effect on respiratory muscle fatigue in chronic obstructive pulmonary disease