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目的:探讨浅表性膀胱肿瘤的治疗方法及其疗效。方法:采用经尿道膀胱肿瘤电气化切除术对36例浅表性膀胱肿瘤患者进行治疗,术后一周开始用α-干扰素加丝裂霉素C膀胱灌注。结果:36例手术均一次获得成功,无严重并发症,手术时间约40分钟,术后不作持续冲洗,留置尿管3-4天,术后一周开始定期灌药,36例全部随访,随访时间6-72个月,有4例于术后于6、9、9、12年月后复发再次行TURBt,术后继续药物灌注,其余32例无复发,无任何药物反应。结论:经尿道膀胱肿瘤电气化切除术,具有操作简单、创伤小、视野清晰、并发症少,可反复进行操作等优点,是治疗浅表性膀胱肿瘤的有效手术方法,而膀胱肿瘤术后复发率较高,约50-70%,术后定期α-干扰素加丝裂霉素C联合灌注有效地阻止了肿瘤的复发,复发率约11.1%。
Objective: To investigate the treatment of superficial bladder tumor and its curative effect. Methods: Thirty-six patients with superficial bladder tumor were treated with electrovaporization of the transurethral bladder tumor. Intraperitoneal injection of α-interferon and mitomycin C was performed one week after the operation. Results: Thirty-six surgeries were successfully performed without any serious complications. The operation time was about 40 minutes. The patients were not continuously rinsed after operation for 3-4 days. The patients were given indwelling catheter for 3-4 days. One week after the operation, all the patients were followed up. All the patients were followed up TURBt occurred again in 6 to 72 months in 4 patients after recurrence at 6, 9, 9 and 12 months. Drug infusion was continued after operation, and the remaining 32 patients had no recurrence and no drug reaction. Conclusions: Electrovaporization of transurethral bladder tumor has the advantages of simple operation, small trauma, clear vision, fewer complications, and repeated operation, which is an effective surgical method for the treatment of superficial bladder tumors. The recurrence rate of bladder tumor Higher, about 50-70%, postoperative regular interferon α and mitomycin C perfusion effectively prevent the recurrence of the tumor, the recurrence rate of about 11.1%.