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目的:分析复方米非司酮联合甲氨蝶呤治疗异位妊娠的临床疗效及安全性。方法:采用随机数字表法选取我院2015年3月至2016年4月间收治的100例异位妊娠患者作为研究对象,分为对照组及观察组,每组各50例。对照组行米非司酮联合甲氨蝶呤治疗,观察组行复方米非司酮联合甲氨蝶呤治疗,对两组患者的最终治疗结果进行观察和统计。结果:观察组患者在治疗有效率、治疗满意度方面明显优于对照组,两组对比具有明显差异,P<0.05,具有统计学意义。观察组不良反应发生率方面与对照组无明显差异,对比无统计学意义(P>0.05)。结论:采用复方米非司酮联合甲氨蝶呤治疗异位妊娠能够较好缓解患者的临床症状、改善阴道流血等情况,缩短附件包块的消失时间,而且不良反应较小,具有较高的应用价值。
Objective: To analyze the clinical efficacy and safety of compound mifepristone and methotrexate in the treatment of ectopic pregnancy. Methods: 100 cases of ectopic pregnancy treated in our hospital from March 2015 to April 2016 were selected as the research object by random number table method and divided into control group and observation group, with 50 cases in each group. The control group was treated with mifepristone combined with methotrexate. The observation group was treated with combination of mifepristone and methotrexate, and the final treatment results of the two groups were observed and statistically analyzed. Results: The observation group was significantly better than the control group in the treatment efficiency and treatment satisfaction, the difference between the two groups was significant (P <0.05), with statistical significance. There was no significant difference between the observation group and the control group in the incidence of adverse reactions, with no significant difference (P> 0.05). Conclusion: The treatment of ectopic pregnancy with compound mifepristone and methotrexate can alleviate the clinical symptoms, improve vaginal bleeding and other conditions, shorten the disappearance of appendages mass, and the adverse reactions are small, with high Value.