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目的:探讨近年来青年女性(≤35岁)胃癌高发的原因、临床病理特点及误诊问题。方法:收集余杭区第二人民医院2000年以来胃镜、病理活检及手术切除胃癌标本共453例,其中青年女性胃癌25例(而青年男性患者为16例),本文对其临床症状、病理诊断及特点、预后及误诊情况作总结分析。结果:青年女性胃癌占同期诊断胃癌患者的5.5%,明显高于男性同年龄组患者,其早期自觉症状不明显,误诊率高。好发于胃窦部,以溃疡型及弥漫型多见,组织类型印戒细胞癌、低分化癌腺为主,恶性程度高,确诊大多已属晚期,预后差。结论:对青年女性胃癌要提高认识,做到早期诊断,早期治疗,减少误诊,提高患者治愈率。
Objective: To investigate the causes, clinicopathological characteristics and misdiagnosis of gastric cancer in young women (≤35 years old) in recent years. Methods: A total of 453 cases of gastric cancer were collected from the Second People ’s Hospital of Yuhang District from 2000 to 1998. There were 25 cases of gastric cancer in young women (compared with 16 cases of young males). The clinical symptoms, pathological diagnosis, Characteristics, prognosis and misdiagnosis of the situation for a summary analysis. Results: The gastric cancer in young women accounted for 5.5% of patients diagnosed with gastric cancer in the same period, which was significantly higher than that of men in the same age group. The early symptoms were not obvious and the rate of misdiagnosis was high. Occur in the antrum, with ulcerative and diffuse more common, tissue type signet ring cell carcinoma, poorly differentiated cancer glands, high degree of malignancy, most of the diagnosed late, poor prognosis. Conclusion: It is necessary to raise awareness of young women with gastric cancer so that they can be diagnosed early and treated early, with less misdiagnosis and higher cure rate.